Our most responsive midsole technology that offers best-in-class energy responsiveness by encasing a polyurethane-based foam inside thermoplastic polyurethane (TPU) skin.
The relationship between running and energy seems simple. As you run, your energy drains. But what if you could get some of that energy back? That’s the goal of Brooks DNA AMP, a midsole technology designed to provide cushioning as well as energy return.
So what is DNA AMP?
DNA AMP is a midsole material that is formulated to absorb the force of your stride and return that energy back to you rather than letting it disperse. That’s why shoes that use DNA AMP feel springy instead of just soft.

What’s DNA AMP made of?
DNA AMP is made of polyurethane (PU) foam encased in a thin layer of thermoplastic polyurethane (TPU). There are tons of ways that PUs and TPUs can be formulated, but we used a PU foam that combines the strength of plastic with rubber’s elasticity. The TPU casing has more rigidity than the foam but still retains some elasticity. The combination of the foam and the casing is what makes DNA AMP feel springy while you’re running.
How does DNA AMP return energy?
Here’s how it works:
- The PU foam responds to the force of your foot, expanding to cushion your stride and absorb the force of your foot hitting the ground.
- Because the foam is surrounded by the more rigid TPU casing, the foam stops expanding at a certain point and the energy is contained.
- Think back to school science class — energy doesn’t just disappear, it has to go somewhere. In this case, where better to send it than back to you?
- The TPU casing helps contain the energy and sends it straight back up for you to absorb.
It’s a complex process, but you can think of it as a high-five between your foot and our running shoe — it’s a boost of energy you get with every step.
How does DNA AMP compare to other Brooks midsoles?
Out of the four current midsole technologies, DNA AMP has the highest energy return, offering a super springy ride — think unleashed puppy in a sea of tennis balls.
- DNA LOFT offers pure softness, for a cloud-like feel that lets you float through your miles.
- BioMoGo DNA is slightly softer than DNA AMP, with less energy return — more playful doggo than crazy pup.
- DNA FLASH is our lightest cushioning. It’s responsive, but doesn’t have the springy pop of DNA AMP. It’s our lightest cushioning. You’ll find DNA FLASH only in our fastest racing and training shoes.
How do you choose?
There’s no wrong choice here, just follow your heart — and your feet — to the experience you want. DNA AMP is the right tech for your run if you like your shoe to feel really bouncy. DNA AMP is also a good fit if you’re looking to add extra energy to your run, especially during tempo runs or workouts.